Hydrating, Collagen boosting injections. A natural alternative to Dermal filler,
with minimal downtime

Achieve smoother, plumper and more youthful-looking skin with our Polynucleotide treatments.


Polynucleotide treatments work by introducing Nucleic acids into the skin, which helps to stimulate Collagen production and improve the elasticity and firmness of the skin. They also help to enhance the natural healing process, promoting tissue regeneration and reducing the appearance of wrinkles, fine lines, scars and redness.

The Nuriss Difference

We offer Polynucleotides as standalone treatments but have also created advanced protocols where we combine Polynucleotides with other technologies such as Morpheus8 3D, our innovative Radiofrequency and Microneedling technology, to ensure that our clients experience the very best results.

Your experience with us will start with a thorough consultation in which we will analyse your skin to ensure it is in an optimal condition for your treatment – this may include a bespoke skincare plan. Your treatment will be performed by highly skilled doctors and nurses with an in-depth understanding of complex facial anatomy. Following your treatment, we guide you on maintenance treatment options to enhance your results

Recommended For:

Everyone with ageing concerns. Treats loss of skin tone, fine lines and wrinkles, skin laxity and dehydration.


Reduces fine lines and wrinkles, improves texture and skin tone.
Collagen remodelling and skin-rejuvenating benefits.


A course of 2- 3 sessions of Polynucleotide treatments are performed every 3-4 weeks. We recommend repeating at least once a year for optimal results.


30-60 minutes depending on the areas to be treated (this is preceded by application of a specialist numbing cream prior to the treatment).

Aftercare and downtime:

Expect to look visibly red and marked for approximately 48 hours.
Keep skin well hydrated and protected with SPF. Prescription Retinol, exfoliation products and vitamin C should not be used for 7 days following treatment.

Discomfort Level:

This treatment is known to be moderately uncomfortable. We can apply topical anaesthesia prior to treatment to address this.

Need to Know:

Results are typically apparent within 1-2 weeks of treatment, deeper change is visible in approximately 12 weeks. It is preferable not to apply heavy make-up immediately following the treatment.


£400 per treatment
£750 course of 2
£1,100 course of 3

Polynucleotide eyes are recommended to be administered over 3 sessions for optimum results

£400 per treatment
£750 course of 2